Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1993-9-10
pubmed:abstractText
The delayed Wallerian degeneration which occurs in the C57BL/Ola mouse is associated with impaired motor axon regeneration. Following sciatic nerve crush, recovery of the sciatic functional index was delayed and incomplete when compared with recovery in C57BL/6J mice. After facial nerve crush, recovery of whisker movement in Ola mice was also delayed, and there was a prolonged period of partial recovery, not seen in 6J mice. Regeneration rate of the motor axons was measured by the axonal transport technique in sciatic nerve and was approximately 0.7 mm/d for Ola mice, and 4.0 mm/d for 6J mice. Combining these results from our previous work, we conclude that regeneration of both sensory and motor axons is impaired when Wallerian degeneration does not follow its usual time course after injury.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0021-9967
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
333
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
449-54
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Impaired motor axon regeneration in the C57BL/Ola mouse.
pubmed:affiliation
Department of Physiology, Queen's University, Kingston, Ontario, Canada.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't