Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1993-9-16
|
| pubmed:abstractText |
Preparation for pelvic exenteration is a traumatic experience for every patient, especially so when the procedure has to be aborted because of advanced disease. This occurred in 111 of 394 patients who underwent exploration for possible pelvic exenteration for recurrent cervical cancer at the University of Texas M. D. Anderson Cancer Center between 1970 and 1990. We reviewed these cases to better delineate preoperative factors predictive of unresectability. Distributions of initial stages and pathological diagnoses were similar to those for all cases of primary cervical cancer. The median time from primary therapy to recurrence was 12 months. The reasons for aborting the procedure included the presence of peritoneal disease in 49 patients (44%), for which the only preoperative finding with significant correlation was the presence of a pelvic mass (P = 0.03). Other reasons for aborting the procedure included nodal disease in 45 patients (40%), related to a short interval from primary therapy (P = 0.008) and the notation of fibrosis on preoperative exam (P = 0.01), parametrial fixation in 15 patients (13%), and hepatic lesions or bowel involvement in 5 patients (4.5%). Peritoneal cytology was negative in 61 of 79 patients (77.2%) and was of predictive value only in patients with adenocarcinoma. In conclusion, disseminated disease can seldom be detected during preoperative work-up. Evaluation of nodal status with computed tomography, lymphangiogram and directed fine-needle aspiration, and examination of peritoneal cytology in cases with adenocarcinoma, are the best available means of reducing the number of aborted procedures.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jul
|
| pubmed:issn |
0090-8258
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
50
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
94-9
|
| pubmed:dateRevised |
2005-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:8349169-Adult,
pubmed-meshheading:8349169-Aged,
pubmed-meshheading:8349169-Cervix Uteri,
pubmed-meshheading:8349169-Female,
pubmed-meshheading:8349169-Forecasting,
pubmed-meshheading:8349169-Humans,
pubmed-meshheading:8349169-Hysterectomy,
pubmed-meshheading:8349169-Intraoperative Period,
pubmed-meshheading:8349169-Lymphatic Metastasis,
pubmed-meshheading:8349169-Middle Aged,
pubmed-meshheading:8349169-Neoplasm Recurrence, Local,
pubmed-meshheading:8349169-Pelvic Exenteration,
pubmed-meshheading:8349169-Peritoneal Neoplasms,
pubmed-meshheading:8349169-Survival Analysis,
pubmed-meshheading:8349169-Time Factors,
pubmed-meshheading:8349169-Uterine Cervical Neoplasms
|
| pubmed:year |
1993
|
| pubmed:articleTitle |
Aborted exenterative procedures in recurrent cervical cancer.
|
| pubmed:affiliation |
Department of Gynecologic Oncology, M. D. Anderson Cancer Center, University of Texas, Houston 77030.
|
| pubmed:publicationType |
Journal Article
|