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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1977-3-21
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pubmed:abstractText |
Androgen insensitivity was demonstrated in two male siblings with partial masculinization of the external genitalia. They had a previously undescribed defect characterized postpubertally by high plasma testosterone and luteinizing hormone concentrations with low serum follicle-stimulating hormone levels. Studies in skin fibroblasts showed normal androgen receptor affinity and capacity for 5alpha-dihydrotestosterone (DHT), normal nuclear retention of the receptor-DHT complex, and normal conversion of testosterone to DHT.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0031-4005
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
59
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
224-31
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:834506-Adult,
pubmed-meshheading:834506-Blood Urea Nitrogen,
pubmed-meshheading:834506-Child,
pubmed-meshheading:834506-Dihydrotestosterone,
pubmed-meshheading:834506-Disorders of Sex Development,
pubmed-meshheading:834506-Dose-Response Relationship, Drug,
pubmed-meshheading:834506-Fibroblasts,
pubmed-meshheading:834506-Follicle Stimulating Hormone,
pubmed-meshheading:834506-Humans,
pubmed-meshheading:834506-Luteinizing Hormone,
pubmed-meshheading:834506-Male,
pubmed-meshheading:834506-Protein Binding,
pubmed-meshheading:834506-Receptors, Androgen,
pubmed-meshheading:834506-Receptors, Steroid,
pubmed-meshheading:834506-Testosterone
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pubmed:year |
1977
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pubmed:articleTitle |
Male pseudohermaphroditism with partial androgen insensitivity.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Case Reports
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