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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
|
| pubmed:dateCreated |
1993-9-9
|
| pubmed:abstractText |
It is known that hematopoiesis is supported by bone-marrow stem cells, but those cells must seed and grow on a stromal microenvironment. Typically, studies have shown that a surviving fraction of about 30 hematopoietic stem cells (HSCs) (i.e., about 0.04%) correspond to the LD50, although other studies have shown that marrow can repopulate from a single viable cell under strong regiments of antibiotics and infusions of irradiated blood elements.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Aug
|
| pubmed:issn |
0360-3016
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
1
|
| pubmed:volume |
26
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
817-30
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:8344851-Animals,
pubmed-meshheading:8344851-Bone Marrow Cells,
pubmed-meshheading:8344851-Cell Survival,
pubmed-meshheading:8344851-Hematopoietic Stem Cells,
pubmed-meshheading:8344851-Likelihood Functions,
pubmed-meshheading:8344851-Mathematics,
pubmed-meshheading:8344851-Mice,
pubmed-meshheading:8344851-Models, Biological,
pubmed-meshheading:8344851-Stromal Cells,
pubmed-meshheading:8344851-Time Factors
|
| pubmed:year |
1993
|
| pubmed:articleTitle |
Mathematical models of marrow cell kinetics: differential effects of protracted irradiations on stromal and stem cells in mice.
|
| pubmed:affiliation |
Health and Safety Research Division, Oak Ridge National Laboratory, TN 37831-6101.
|
| pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, Non-P.H.S.
|