Linked Life Data

8344684

Source:http://linkedlifedata.com/resource/pubmed/id/8344684

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1993-9-9
pubmed:abstractText
The intestinal immune system has to protect the mucosa against microbial and toxic agents. This is achieved by elimination of potential antigens, which are inhibited to adhere and to invade the mucosa. Thus, induction of inflammatory processes is prevented. Elimination of antigens is mediated by the secretion and transport of IgA (and especially IgA2) to the lumen of the gut. There, IgA is the most efficient part of the so-called "mucosa block". The composition of mononuclear cells in the lamina propria exhibits the preference of a memory T cell type that is able to provide help for B cells. If IgA-mediated immune response proves not to be sufficient, IgG-mediated inflammatory processes are induced within the mucosa. The role of cytotoxic T cells and, moreover, the biological function of intraepithelial lymphocytes are still controversial.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0340-1162
pubmed:author
pubmed:issnType
Print
pubmed:volume
21 Suppl 1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
31-3
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
[The mucosa-associated immune system--immune defense in the gastrointestinal tract].
pubmed:affiliation
Medizinische Kern- und Poliklinik, Universitäts-Krankenhaus Eppendorf, Hamburg.
pubmed:publicationType
Journal Article, English Abstract, Review