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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
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pubmed:dateCreated |
1993-9-7
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pubmed:abstractText |
The symptom index is a quantitative measure developed for assessing the relationship between gastroesophageal reflux and symptoms. Controversy exists, however, over its accuracy and the appropriate threshold for defining acid-related symptoms of heartburn and chest pain. Therefore, a retrospective review was done of 153 consecutive patients referred to our esophageal laboratory. Three groups were identified: patients with normal 24-hr pH tests and no esophagitis, patients with abnormal 24-hr pH tests and no esophagitis, and patients with abnormal 24 hr pH values and endoscopic esophagitis. If symptoms occurred during the pH study, a symptom index (number of acid related symptoms/total number of symptoms x 100%) was calculated separately for heartburn and chest pain. Heartburn and chest pain episodes were similar among the three groups. However, the mean symptom index for heartburn was significantly (P < 0.001) higher in the patient groups with abnormal pH values [abnormal pH/no esophagitis: 70 +/- 7.1% (+/- SE); abnormal pH/esophagitis: 85 +/- 4.6%] as compared to those with normal studies, ie, functional heartburn (26 +/- 10.7%). The mean symptom index for chest pain was similar for all three groups. Using receiver operating characteristic curves, a heartburn symptom index > or = 50% had excellent sensitivity (93%) and good specificity (71%) for acid reflux disease, especially if patients complain of multiple episodes of heartburn. In contrast, an optimal symptom index threshold for defining acid-related chest pain episodes could not be defined.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0163-2116
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
38
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1402-8
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:8344094-Adult,
pubmed-meshheading:8344094-Aged,
pubmed-meshheading:8344094-Chest Pain,
pubmed-meshheading:8344094-Esophagitis,
pubmed-meshheading:8344094-Esophagoscopy,
pubmed-meshheading:8344094-Female,
pubmed-meshheading:8344094-Gastroesophageal Reflux,
pubmed-meshheading:8344094-Heartburn,
pubmed-meshheading:8344094-Humans,
pubmed-meshheading:8344094-Hydrogen-Ion Concentration,
pubmed-meshheading:8344094-Male,
pubmed-meshheading:8344094-Middle Aged,
pubmed-meshheading:8344094-ROC Curve,
pubmed-meshheading:8344094-Retrospective Studies,
pubmed-meshheading:8344094-Sensitivity and Specificity,
pubmed-meshheading:8344094-Severity of Illness Index
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pubmed:year |
1993
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pubmed:articleTitle |
The symptom index. Differential usefulness in suspected acid-related complaints of heartburn and chest pain.
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pubmed:affiliation |
Division of Gastroenterology, University of Alabama, Birmingham 35294.
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pubmed:publicationType |
Journal Article
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