Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1993-8-30
pubmed:abstractText
We describe the clinical, structural, and immunophenotypic characteristics of a lymphoproliferative process characterized by persistent thrombocytopenia and prominent involvement of the spleen and, to a lesser degree, the liver. The proliferating cells lacked cytoplasmic azurophilic granules by light microscopy and on ultrastructural examination displayed prominent interdigitating cell processes and did not contain parallel tubular arrays. Immunophenotypically, the cells displayed markers of true natural killer cells (positive CD2, CD56, CD45, CD7, CD16, and CD33). No involvement of peripheral blood or bone marrow was detected. This case represents a proliferation of true natural killer cells probably arising in the spleen. The relationship of this process to other lymphoid proliferations at different sites with true natural killer cell or natural killer-like activity is unknown.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0003-9985
pubmed:author
pubmed:issnType
Print
pubmed:volume
117
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
851-5
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Lymphoproliferative process with natural killer cell phenotype. Histopathologic, ultrastructural, and surface marker observations.
pubmed:affiliation
Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis.
pubmed:publicationType
Journal Article, Case Reports