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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1993-8-20
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pubmed:abstractText |
A new instrument using the laser speckle phenomenon for noninvasive 2-dimensional analysis of the choroidal microcirculation was developed. The fundus was illuminated with a diode laser spot and its image speckle was detected with an area sensor. The difference between the average of the output data (I-mean) and the output data from successive scannings of the image speckles at the sensor plane was calculated and integrated to give as D-mean, and I-mean/D-mean was defined as normalized blur (NB), which is a quantitative index of blood flow velocity. The results were displayed in color graphics showing the 2-dimensional variation of the NB level in the area of interest. The NB had good correlation with the speed measured on ground glass in the range between 2 and 130mm/sec. Using this instrument, the effect of intraocular pressure on the chroidal circulation of the rabbit was studied. The coefficient of reproducibility was 6.9% when measured in the same area twice at 5-minute intervals. A stepwise reduction in the ocular perfusion pressure was introduced by elevating the intraocular pressure manometrically. A linear correlation was found between the NB and the ocular perfusion pressure.
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pubmed:language |
jpn
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0029-0203
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
97
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
602-9
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pubmed:dateRevised |
2011-7-28
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pubmed:meshHeading |
pubmed-meshheading:8337964-Animals,
pubmed-meshheading:8337964-Blood Flow Velocity,
pubmed-meshheading:8337964-Choroid,
pubmed-meshheading:8337964-Intraocular Pressure,
pubmed-meshheading:8337964-Laser-Doppler Flowmetry,
pubmed-meshheading:8337964-Microcirculation,
pubmed-meshheading:8337964-Rabbits
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pubmed:year |
1993
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pubmed:articleTitle |
[An apparatus using laser speckle phenomenon for noninvasive 2-dimensional analysis of choroidal microcirculation].
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pubmed:affiliation |
Eye Clinic, Tokyo Metropolitan Geriatric Hospital, Itabashi-ku, Japan.
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pubmed:publicationType |
Journal Article,
English Abstract
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