Linked Life Data

8337722

Source:http://linkedlifedata.com/resource/pubmed/id/8337722

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1993-8-25
pubmed:abstractText
Testing for antibodies to human immunodeficiency virus (HIV) in urine may be of use in epidemiological studies. We collected 336 paired urine and serum samples from subjects in Karonga District, northern Malawi: 86 (25.6%) of the serum samples were HIV positive. Serum results were compared with those from immunoglobulin (Ig) G antibody-capture particle adherence tests (GACPAT) and IgG antibody-capture enzyme-linked immunosorbent assay (GACELISA) on the corresponding urine samples performed independently in 2 laboratories. The minimum observed relative sensitivity and specificity of GACPAT were 96.5% and 98.8% respectively; the specificity could be raised by using a protocol involving re-testing of reactive samples to determine end-point titre. For GACELISA, the observed relative sensitivity and specificity were 98.8% and 99.2% respectively. Such assays may be useful either as a primary screen in populations where urine samples are considerably easier to obtain than serum samples, or as an alternative test for individuals unwilling to provide a serum sample.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0035-9203
pubmed:author
pubmed:issnType
Print
pubmed:volume
87
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
181-3
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
Human immunodeficiency virus: GACPAT and GACELISA as diagnostic tests for antibodies in urine.
pubmed:affiliation
Communicable Disease Epidemiology Unit, London School of Hygiene and Tropical Medicine, UK.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't