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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1993-8-24
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pubmed:abstractText |
The prevalence of Chlamydia infection in 95 sex partners was determined by both polymerase chain reaction (PCR) and cell culture. Thirty-three (18%) of 186 specimens were positive by culture and 61 (33%) were positive by PCR-EIA. PCR was positive in 75% (21/28) of male partners of PCR-positive women compared with culture, which was positive in only 45% (9/19) of male partners of culture-positive women (P = .053). For female partners of infected men, the difference was less marked. PCR was positive in 58% (21/36) of female partners of infected men versus culture, which was positive in 56% (15/36) of female partners of culture-positive men. The correlation of PCR between partners and sequence analysis of Chlamydia DNA showing the same sequence from sex partners of 7 couples support the accuracy of the assay. These data suggest that PCR is more sensitive than culture for detection of Chlamydia trachomatis, particularly for male partners of infected women.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0022-1899
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
168
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
488-92
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:8335993-Adult,
pubmed-meshheading:8335993-Base Sequence,
pubmed-meshheading:8335993-Cells, Cultured,
pubmed-meshheading:8335993-Chlamydia Infections,
pubmed-meshheading:8335993-DNA, Bacterial,
pubmed-meshheading:8335993-Female,
pubmed-meshheading:8335993-Humans,
pubmed-meshheading:8335993-Immunoenzyme Techniques,
pubmed-meshheading:8335993-Male,
pubmed-meshheading:8335993-Molecular Sequence Data,
pubmed-meshheading:8335993-Polymerase Chain Reaction,
pubmed-meshheading:8335993-Sexual Partners
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pubmed:year |
1993
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pubmed:articleTitle |
Transmission of Chlamydia trachomatis among sex partners assessed by polymerase chain reaction.
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pubmed:affiliation |
Division of Infectious Diseases (Department of Pediatrics), Johns Hopkins University School of Medicine, Baltimore, Maryland.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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