Linked Life Data

8335162

Source:http://linkedlifedata.com/resource/pubmed/id/8335162

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1993-8-23
pubmed:abstractText
The authors report the case of a young boy with macrocephaly, cerebellar symptoms and signs of raised intracranial pressure. Magnetic resonance imaging showed obstruction of the aqueduct, ventricular enlargement of the cerebellum and areas of increased signal intensity in the cerebellar and frontal white matter. A stereotactic biopsy of the cerebellum showed many Rosenthal fibres and glial proliferation. Although the histopathological and neuroradiological findings were suggestive of Alexander's disease, the initial presentation and clinical course were unusual for this diagnosis. The authors suggest that a separate form of Alexander's disease should be distinguished with predominant clinical, neuroradiological and neuropathological cerebellar involvement. This form also seems to have a better life-expectancy.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0012-1622
pubmed:author
pubmed:issnType
Print
pubmed:volume
35
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
732-6
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
A case of macrocephaly, hydrocephalus, megacerebellum, white matter abnormalities and Rosenthal fibres.
pubmed:affiliation
Department of Neurosurgery, University Hospital, Amsterdam.
pubmed:publicationType
Journal Article, Case Reports