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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1993-8-16
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pubmed:abstractText |
The association between diet and the 25-year incidence of chronic nonspecific lung diseases (CNSLD) was studied in 793 middle-aged men in the town of Zutphen, the Netherlands, in 1960-1985. During follow-up, 232 new cases of CNSLD were identified. The incidence rate was 14.1 per 1,000 person-years. Habitual food intake was assessed by the cross-check dietary history method. The intake of linoleic acid was positively associated with the incidence of CNSLD. The relative risk was 1.55 (95% confidence interval (Cl) 1.11-2.16), comparing the highest with the lowest quartile of intake of linoleic acid, independent of potential cofounders (age, cigarette smoking, body mass index, and energy intake). Alcohol consumers showed a significantly lower risk than did non-consumers (relative risk (RR) = 0.72, 95% Cl 0.55-0.95) after adjustment for confounders. In addition, fruit intake was inversely related to incidence of CNSLD (RR = 0.73, 95% Cl 0.53-0.99). No association was observed with intake of several antioxidants. These results suggest that in addition to well-established determinants, such as cigarette smoking and occupational exposure, dietary factors may play a role in the onset of chronic nonspecific lung diseases.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0002-9262
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
138
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
37-45
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:8333425-Adult,
pubmed-meshheading:8333425-Alcohol Drinking,
pubmed-meshheading:8333425-Diet,
pubmed-meshheading:8333425-Fatty Acids, Unsaturated,
pubmed-meshheading:8333425-Fruit,
pubmed-meshheading:8333425-Humans,
pubmed-meshheading:8333425-Incidence,
pubmed-meshheading:8333425-Longitudinal Studies,
pubmed-meshheading:8333425-Lung Diseases, Obstructive,
pubmed-meshheading:8333425-Male,
pubmed-meshheading:8333425-Middle Aged,
pubmed-meshheading:8333425-Netherlands,
pubmed-meshheading:8333425-Risk Factors
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pubmed:year |
1993
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pubmed:articleTitle |
Dietary determinants of long-term incidence of chronic nonspecific lung diseases. The Zutphen Study.
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pubmed:affiliation |
Department of Chronic Diseases and Environmental Epidemiology, National Institute of Public Health and Environmental Protection, Bilthoven, The Netherlands.
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pubmed:publicationType |
Journal Article
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