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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
1993-8-17
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pubmed:abstractText |
Although the frequency of preoperative autologous blood donation is increasing dramatically, the economic implications of its use remain largely unexplored. Decision analysis was used to calculate the cost-effectiveness of autologous blood donation for hip and knee replacement. Cost-effectiveness, expressed as cost per quality-adjusted year of life saved, was based on observed red cell use in 629 patients undergoing surgery at two tertiary-care centers. Autologous blood donation for bilateral and revision joint replacement cost $40,000 per quality-adjusted year of life saved at Center 1 and $241,000 at Center 2. Autologous blood donation for primary unilateral hip replacement cost $373,000 per quality-adjusted year of life saved at Center 1 and $740,000 at Center 2. Autologous blood donation was least cost-effective for primary unilateral knee replacement ($1,147,000/quality-adjusted year of life saved at Center 1 and $1,467,000/year at Center 2). Differences between autologous blood collections and transfusion requirements explained variations among procedures in the cost-effectiveness of autologous blood donation. Higher transfusion rates in autologous blood donors than in nondonors accounted for the poorer cost-effectiveness of autologous blood donation at Center 2 than at Center 1. Autologous blood donation is not as cost-effective as most accepted medical practices. Its cost-effectiveness can be improved substantially by the avoidance of overcollection and overtransfusion of autologous blood.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0041-1132
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
33
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
544-51
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:8333017-Blood Donors,
pubmed-meshheading:8333017-Blood Transfusion, Autologous,
pubmed-meshheading:8333017-Cost-Benefit Analysis,
pubmed-meshheading:8333017-Decision Making,
pubmed-meshheading:8333017-Hip Prosthesis,
pubmed-meshheading:8333017-Hospitals, University,
pubmed-meshheading:8333017-Humans,
pubmed-meshheading:8333017-Knee Prosthesis,
pubmed-meshheading:8333017-New Hampshire,
pubmed-meshheading:8333017-Quality of Life,
pubmed-meshheading:8333017-Value of Life
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pubmed:year |
1993
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pubmed:articleTitle |
The cost-effectiveness of preoperative autologous blood donation for total hip and knee replacement.
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pubmed:affiliation |
Department of Surgery, Dartmouth-Hitchcock Medical Center, Lebanon, NH.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|