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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1-2
|
pubmed:dateCreated |
1993-8-16
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pubmed:abstractText |
Based on our previous finding of elevated interferon-gamma levels in the cerebrospinal fluid (CSF), but not in serum, of HTLV-I-associated myelopathy (HAM), we assayed serum and CSF levels of granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-1 (IL-1) and tumor necrosis factor-alpha (TNF-alpha) in 20 HAM. GM-CSF and IL-1 also increased only in the CSF in 75% and 35%, respectively, of 20 HAM. TNF-alpha was not detected in any of the sera and CSFs. Multiple cytokines may be produced in the central nervous system and play an important role in HAM.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0165-5728
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
45
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
133-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8331158-Adult,
pubmed-meshheading:8331158-Aged,
pubmed-meshheading:8331158-Female,
pubmed-meshheading:8331158-Granulocyte-Macrophage Colony-Stimulating Factor,
pubmed-meshheading:8331158-Humans,
pubmed-meshheading:8331158-Interleukin-1,
pubmed-meshheading:8331158-Male,
pubmed-meshheading:8331158-Middle Aged,
pubmed-meshheading:8331158-Paraparesis, Tropical Spastic,
pubmed-meshheading:8331158-Reference Values,
pubmed-meshheading:8331158-Tumor Necrosis Factor-alpha
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pubmed:year |
1993
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pubmed:articleTitle |
Granulocyte-macrophage colony-stimulating factor and interleukin-1 increase in cerebrospinal fluid, but not in serum, of HTLV-I-associated myelopathy.
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pubmed:affiliation |
Department of Internal Medicine (Section of Neurology), Saga Medical School, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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