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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1993-8-19
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pubmed:abstractText |
Twenty-eight consecutive patients submitted to radical nephrectomy for Robson's stage II-III renal cell carcinoma underwent adjuvant recombinant a-2b interferon, 5 MUI s.c. 3 times a week, for 6 consecutive months. Home-feasibility of this therapy resulted easy. The most frequent acute (flu-like syndrome) and late (myalgia, fatigue, anorexia) side effects did not affect normal daily life of patients. Eight (28.5%) patients had WHO grade < or = 2 biochemical and hematological toxicity, that normalized after a reduction or a temporarily suspension of therapy. Twenty-seven patients were evaluable for response. Out of these, 7 (26%) relapsed after a 16 months median follow-up.
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pubmed:language |
ita
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
|
pubmed:issn |
1124-3562
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
65
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pubmed:owner |
NLM
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pubmed:authorsComplete |
N
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pubmed:pagination |
173-6
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:8330063-Adult,
pubmed-meshheading:8330063-Aged,
pubmed-meshheading:8330063-Carcinoma, Renal Cell,
pubmed-meshheading:8330063-Feasibility Studies,
pubmed-meshheading:8330063-Female,
pubmed-meshheading:8330063-Follow-Up Studies,
pubmed-meshheading:8330063-Humans,
pubmed-meshheading:8330063-Immunologic Factors,
pubmed-meshheading:8330063-Interferon-alpha,
pubmed-meshheading:8330063-Kidney Neoplasms,
pubmed-meshheading:8330063-Male,
pubmed-meshheading:8330063-Middle Aged,
pubmed-meshheading:8330063-Nephrectomy,
pubmed-meshheading:8330063-Pilot Projects,
pubmed-meshheading:8330063-Recombinant Proteins,
pubmed-meshheading:8330063-Risk,
pubmed-meshheading:8330063-Treatment Outcome
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pubmed:year |
1993
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pubmed:articleTitle |
[Adjuvant interferon alpha in renal carcinoma with a high risk of recurrence. Multicenter pilot study].
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pubmed:affiliation |
Istituto Nazionale Tumori, Milano.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
English Abstract,
Multicenter Study
|