Linked Life Data

8329188

Source:http://linkedlifedata.com/resource/pubmed/id/8329188

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1993-8-19
pubmed:abstractText
Prevention of postoperative adhesion is an issue that continues to elude the abdominal and reproductive surgeon. Adhesions seem to be a result of an inflammatory process and it is well known that prostaglandins play an important role in such an event. In an attempt to improve the results of microsurgery, we have tried in this study to examine the effect of local intraperitoneal application of prostaglandins (PGE2 and PGF2 alpha) on adhesion formation in the rat after traumatizing to the uterine horn. Prostaglandins applied locally were found to increase intraperitoneal adhesion formation at the injured sites, in comparison with controls. Also, we have reported on histological examination an increased accumulation of inflammatory cells in traumatized areas. However, we didn't observe a reduced fertility in rats treated with prostaglandins because these substances induce follicular rupture by activation of proteolytic enzyme located in the follicular wall. We conclude that prostaglandins play an important role in the process of adhesion formation. Using antiprostaglandins agents could improve the outcomes of reproductive surgery.
pubmed:language
ita
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0037-8771
pubmed:author
pubmed:issnType
Print
pubmed:volume
69
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
33-8
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
[The role of prostaglandins in fertility. Experimental research].
pubmed:affiliation
I Clinica Ostetrica e Ginecologica P. Sfameni, Università degli Studi di Bologna.
pubmed:publicationType
Journal Article, Comparative Study, English Abstract