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pubmed-article:8324843pubmed:abstractTextThe model of precancerous lesions of the bladder in rats was induced by N-butyl-(4-hydroxybutyl) nitrosamide (BBN). The animals were randomly divided into the following 3 groups: 1) given Antitumor-B (Chinese herbs); 2) given 4-ethoxycarbophenylretinamide (Retinamide); and 3) control. After treatment for 13 months the rats were killed for pathomorphological examination of the bladder. The results showed that the incidence of bladder cancer in group 1 and 2 was reduced by 90.7% (P < 0.01) and 75.0% (P < 0.01) respectively after treatment as compared with the control group. Our results provide a useful reference for clinical trial in the prevention of bladder cancer recurrence by using antitumor-B and Retinamide.lld:pubmed
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pubmed-article:8324843pubmed:year1993lld:pubmed
pubmed-article:8324843pubmed:articleTitle[Inhibitory effect of antitumor-B and retinamide on precancerous lesions of the bladder in rats].lld:pubmed
pubmed-article:8324843pubmed:affiliationInstitute of Oncology, Beijing.lld:pubmed
pubmed-article:8324843pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:8324843pubmed:publicationTypeEnglish Abstractlld:pubmed