|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
1
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|
pubmed:dateCreated |
1993-8-12
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|
pubmed:abstractText |
The model of precancerous lesions of the bladder in rats was induced by N-butyl-(4-hydroxybutyl) nitrosamide (BBN). The animals were randomly divided into the following 3 groups: 1) given Antitumor-B (Chinese herbs); 2) given 4-ethoxycarbophenylretinamide (Retinamide); and 3) control. After treatment for 13 months the rats were killed for pathomorphological examination of the bladder. The results showed that the incidence of bladder cancer in group 1 and 2 was reduced by 90.7% (P < 0.01) and 75.0% (P < 0.01) respectively after treatment as compared with the control group. Our results provide a useful reference for clinical trial in the prevention of bladder cancer recurrence by using antitumor-B and Retinamide.
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pubmed:language |
chi
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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|
pubmed:month |
Feb
|
|
pubmed:issn |
1000-503X
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pubmed:author |
|
|
pubmed:issnType |
Print
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|
pubmed:volume |
15
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
71-3
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|
pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8324843-Animals,
pubmed-meshheading:8324843-Antineoplastic Agents, Phytogenic,
pubmed-meshheading:8324843-Butylhydroxybutylnitrosamine,
pubmed-meshheading:8324843-Carcinoma, Transitional Cell,
pubmed-meshheading:8324843-Drugs, Chinese Herbal,
pubmed-meshheading:8324843-Precancerous Conditions,
pubmed-meshheading:8324843-Rats,
pubmed-meshheading:8324843-Rats, Wistar,
pubmed-meshheading:8324843-Tretinoin,
pubmed-meshheading:8324843-Urinary Bladder Neoplasms
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|
pubmed:year |
1993
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|
pubmed:articleTitle |
[Inhibitory effect of antitumor-B and retinamide on precancerous lesions of the bladder in rats].
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pubmed:affiliation |
Institute of Oncology, Beijing.
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|
pubmed:publicationType |
Journal Article,
English Abstract
|
