Linked Life Data

8322500

Source:http://linkedlifedata.com/resource/pubmed/id/8322500

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1993-8-5
pubmed:abstractText
The purpose of this investigation has been to demonstrate the safety of temperature controlled angioplasty (TCA) with a coaxial heating element, particularly during heat application, and to ascertain the short- and long-term arterial tissue response in 7 month old homozygous Heritable Hyperlipidemic rabbits. In 7 animals, a defined segment of the abdominal aorta was treated with TCA for 40 seconds at 175 degrees C, and 2 animals served as untreated controls. At sacrifice, 1 day, 1 and 2 weeks after TCA, in one animal each a coagulation necrosis with condensation of elastic fibers was found. One year later, 1 of 2 animals revealed irregularly structured elastic fibers combined with only minor atherosclerotic lesions. Treated segments of the second animal and of the 2 remaining animals 2 years after TCA did not appear to differ from the control segments. In conclusion, the TCA never resulted in perforation or carbonization or in adhesion of the heating element to the vascular wall, representing a safe angioplastic technique.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0301-1526
pubmed:author
pubmed:issnType
Print
pubmed:volume
22
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
124-8
pubmed:dateRevised
2008-2-13
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Temperature controlled angioplasty (preliminary results in heritable hyperlipidemic rabbits).
pubmed:affiliation
Klinik für Chirurgie, Medizinische Universität zu Lübeck.
pubmed:publicationType
Journal Article