Linked Life Data

8319401

Source:http://linkedlifedata.com/resource/pubmed/id/8319401

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1993-8-3
pubmed:abstractText
Reinjection of a second dose of Tl-201 before redistribution imaging has significantly improved the ability of myocardial perfusion imaging to detect jeopardized myocardium. However, PET studies and the results from coronary artery angioplasty and bypass surgery indicate that Tl-201 studies still underestimate the number of ischemic areas at stress that represent viable myocardium. To determine whether an imaging protocol using an early reinjection of Tl-201 immediately after acquisition of the stress images would improve the detection of jeopardized myocardium, 138 patients were studied with an early reinjection protocol and the incidence and magnitude of reversible defects were compared by SPECT to a second group of 143 patients who underwent the standard late reinjection protocol. Two observers independently evaluated 19 standard myocardial segments by visual examination in each patient. They determined the presence or absence of reversible defects, and, when present, their magnitude. The frequency of reversible defects always was less with early reinjection compared to the standard late reinjection; the difference reached statistical significance for one of the two observers (P < 0.05). It is concluded that early reinjection of Tl-201 in myocardial perfusion imaging does not increase and may decrease the sensitivity of the study for jeopardized myocardium.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0363-9762
pubmed:author
pubmed:issnType
Print
pubmed:volume
18
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
487-90
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Detection of jeopardized myocardium with Tl-201 myocardial perfusion imaging. Comparison of early and late reinjection protocols.
pubmed:affiliation
Department of Radiology, Porter Memorial Hospital, Denver, Colorado.
pubmed:publicationType
Journal Article, Comparative Study