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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1993-7-28
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pubmed:abstractText |
Pretreatment serum levels of soluble interleukin-2 receptor (sIL-2R), CA 125, and SCC were measured in 183 patients with malignant or benign uterine diseases. Serum sIL-2R levels were higher in the 46 patients with cervical cancer (p < 0.05) or in the 35 patients with endometrial cancer (p < 0.05) than in the 102 patients with benign uterine diseases. Raised serum concentrations of sIL-2R (> or = 50 U/mL), CA 125 (> or = 35 U/mL) and SCC (> or = 2 ng/mL) were found in 50.0%, 15.0% and 67.5% of 40 patients with squamous cell carcinoma of the cervix, respectively. Serum sIL-2R values were > or = 50 U/mL in 83.3% of 6 patients with cervical adenocarcinoma. Elevated serum levels of sIL-2R, CA 125 and SCC were detected in 51.4%, 11.3% and 14.3% of 35 patients with endometrial cancer, respectively. The sensitivity of SCC for squamous cell carcinoma of the cervix was better than that of sIL-2R. On the other hand, we observed that sIL-2R was the most sensitive antigen for endometrial cancer; therefore it could represent a new tumor marker for the management of patients with this malignancy.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Neoplasm,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Tumor-Associated...,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Interleukin-2,
http://linkedlifedata.com/resource/pubmed/chemical/Serpins,
http://linkedlifedata.com/resource/pubmed/chemical/squamous cell carcinoma-related...
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pubmed:status |
MEDLINE
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pubmed:issn |
0250-7005
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
13
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
709-13
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pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:8317901-Adenocarcinoma,
pubmed-meshheading:8317901-Adult,
pubmed-meshheading:8317901-Aged,
pubmed-meshheading:8317901-Aged, 80 and over,
pubmed-meshheading:8317901-Antigens, Neoplasm,
pubmed-meshheading:8317901-Antigens, Tumor-Associated, Carbohydrate,
pubmed-meshheading:8317901-Carcinoma, Squamous Cell,
pubmed-meshheading:8317901-Endometrial Neoplasms,
pubmed-meshheading:8317901-Female,
pubmed-meshheading:8317901-Humans,
pubmed-meshheading:8317901-Middle Aged,
pubmed-meshheading:8317901-Neoplasm Staging,
pubmed-meshheading:8317901-Receptors, Interleukin-2,
pubmed-meshheading:8317901-Retrospective Studies,
pubmed-meshheading:8317901-Serpins,
pubmed-meshheading:8317901-Uterine Cervical Neoplasms,
pubmed-meshheading:8317901-Uterine Diseases
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pubmed:articleTitle |
Serum soluble interleukin-2 receptor (sIL-2R) assay in cervical and endometrial cancer. Preliminary data.
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pubmed:affiliation |
Istituto di Medicina Nucleare, Università di Pisa, Italy.
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pubmed:publicationType |
Journal Article
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