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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1994-3-22
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pubmed:abstractText |
Gangliosides, glycosphingolipids with sialic acid, were found in metacestodes of Echinococcus multilocularis in low quantities. All gangliosides were resolved after preparative high-performance thin layer chromatography into four fractions. Cholera toxin was specifically bound to the major ganglioside, allowing the identification of it as a GM1. Precise structure of the four fractions was determined by sequential degradation by exoglycosidases, gas chromatography, electron impact mass spectrometry and liquid secondary ion-mass spectrometry. Beside GM1, the other fractions were GM3, GD1a and, at a lesser percentage, GM2, all belonging to the same a-ganglio-series. The ceramide part of these parasite gangliosides contained sphingosine associated to unsaturated n24, saturated n24 and n16 fatty acids.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Fatty Acids,
http://linkedlifedata.com/resource/pubmed/chemical/Gangliosides,
http://linkedlifedata.com/resource/pubmed/chemical/Glycoside Hydrolases,
http://linkedlifedata.com/resource/pubmed/chemical/Neuraminidase,
http://linkedlifedata.com/resource/pubmed/chemical/Sphingosine,
http://linkedlifedata.com/resource/pubmed/chemical/ceramide glycanase
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0006-3002
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
22
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pubmed:volume |
1225
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
297-303
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8312377-Animals,
pubmed-meshheading:8312377-Carbohydrate Sequence,
pubmed-meshheading:8312377-Echinococcus,
pubmed-meshheading:8312377-Fatty Acids,
pubmed-meshheading:8312377-Gangliosides,
pubmed-meshheading:8312377-Glycoside Hydrolases,
pubmed-meshheading:8312377-Molecular Sequence Data,
pubmed-meshheading:8312377-Neuraminidase,
pubmed-meshheading:8312377-Sphingosine
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pubmed:year |
1994
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pubmed:articleTitle |
Gangliosides of Echinococcus multilocularis metacestodes.
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pubmed:affiliation |
Département de Parasitologie et Pathologie Exotique, Université Claude Bernard, Lyon, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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