Linked Life Data

8303307

Source:http://linkedlifedata.com/resource/pubmed/id/8303307

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4 Suppl 4
pubmed:dateCreated
1994-3-9
pubmed:abstractText
T lymphocytes play a critical role in host immunity, autoimmunity, and tissue rejection. There has been tremendous progress in understanding the molecular basis of T-cell recognition of foreign and self antigens. It is now well established that the major histocompatibility complex (MHC)-restricted nature of T-cell recognition is due to the interaction of the T-cell antigen receptor with MHC class I or II molecules bearing short peptides derived from antigenic proteins. In this report, we review recent progress in understanding antigen processing, ie, the mechanism by which antigenic peptides are generated in antigen-presenting cells and delivered to the appropriate MHC molecule in the appropriate intracellular compartment.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0037-1963
pubmed:author
pubmed:issnType
Print
pubmed:volume
30
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
26-32; discussion 33-4
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Antigen processing: a critical factor in rational vaccine design.
pubmed:affiliation
Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892.
pubmed:publicationType
Journal Article, Review