Linked Life Data

8302037

Source:http://linkedlifedata.com/resource/pubmed/id/8302037

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4B
pubmed:dateCreated
1994-3-7
pubmed:abstractText
We have reviewed highlights of the research in trabecular bone biomechanics performed over the past 20 years. Results from numerous studies have shown that trabecular bone is an extremely heterogeneous material--modulus can vary 100-fold even within the same metaphysis--with varying degrees of anisotropy. Strictly speaking, descriptions of the mechanical properties of trabecular bone should therefore be accompanied by specification of factors such as anatomic site, loading direction, and age. Research efforts have also been focused on the measurement of mechanical properties for individual trabeculae, improvement of methods for mechanical testing at the continuum level, quantification of the three-dimensional architecture of trabecular bone, and formulation of equations to relate the microstructural and continuum-level mechanical properties. As analysis techniques become more sophisticated, there is now evidence that factors such as anisotropy and heterogeneity of individual trabeculae might also have a significant effect on the continuum-level properties, suggesting new directions for future research. Other areas requiring further research are the time-dependent and multiaxial failure properties at the continuum level, and the stiffness and failure properties at the lamellar level. Continued research in these areas should enhance our understanding of issues such as age-related bone fracture, prosthesis loosening, and bone remodeling.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0148-0731
pubmed:author
pubmed:issnType
Print
pubmed:volume
115
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
534-42
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
A 20-year perspective on the mechanical properties of trabecular bone.
pubmed:affiliation
Department of Orthopaedic Surgery, Charles A. Dana Research Institute, Beth Israel Hospital, Boston, MA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Review, Research Support, Non-U.S. Gov't