Linked Life Data

829493

Source:http://linkedlifedata.com/resource/pubmed/id/829493

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1977-11-25
pubmed:abstractText
Inhalation studies were undertaken in which plutonium dioxide (239PuO2) was administered to either unanesthetized Wistar rats or anaesthetized baboons. In both groups of animals some deaths occurred from acute lung damage resulting from cell necrosis particularly to vascular tissue followed by alveolar oedema. At later stages, marked interstitial pneumonitis and interstitial fibrosis occurred and deaths resulted from respiratory insufficiency preceded by high arterial blood pCO2 and low pO2. In rats as many as 50% of the animals finally developed lung neoplasms by only two such tumours were found in baboons. Attempts were made to correlate biochemical parameters with observed tissue damage and animal mortality.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0301-1577
pubmed:author
pubmed:issnType
Print
pubmed:volume
4 Pt 2
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
583-95
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1975
pubmed:articleTitle
239PuO2 aerosol inhalation with emphasis on pulmonary connective tissue modifications.
pubmed:publicationType
Journal Article