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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:dateCreated |
1977-10-31
|
| pubmed:abstractText |
In order to test the therapeutic efficiency of intravenous PVNO injections against anthracosilicotic changes, long-term inhalation tests were performed in which rhesus monkeys were exposed to coal-quartz dust. The exposures were given over a period of 48 months. PVNO treatment at a concentration of 300 or 600 mg/kg body weight began 8 months after the end of exposure. To determine the effect of PVNO injections, hydroxyproline examinations of the urine were made. After a total duration of 70 months the test was followed by an examination of respiration and circulation. In addition to histological check-ups the organ weights were determined. Under the influence of PVNO treatment neither a regression of anthracosilicotic changes in lungs and lung lymph nodes occurred nor was the progression of these changes retarded.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Sep
|
| pubmed:issn |
0301-1577
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
4 Pt 1
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
379-87
|
| pubmed:dateRevised |
2003-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:829443-Animals,
pubmed-meshheading:829443-Anthracosilicosis,
pubmed-meshheading:829443-Female,
pubmed-meshheading:829443-Haplorhini,
pubmed-meshheading:829443-Hydroxyproline,
pubmed-meshheading:829443-Macaca mulatta,
pubmed-meshheading:829443-Polyvinylpyridine N-Oxide,
pubmed-meshheading:829443-Polyvinyls,
pubmed-meshheading:829443-Time Factors
|
| pubmed:year |
1975
|
| pubmed:articleTitle |
Long-term test on rhesus monkeys for the PVNO therapy of anthracosilicosis.
|
| pubmed:publicationType |
Journal Article
|