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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3-4
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pubmed:dateCreated |
1994-2-22
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pubmed:abstractText |
This study characterizes the naturally occurring feline alloantibodies against A and B blood type. All examined type-A and type-B cats had naturally occurring antibodies against erythrocytes of the opposite blood type. In order to determine the class of immunoglobulins, sera from cats were analyzed using incubation with 2-mercaptoethanol (2-ME), immunoprecipitation, and gel filtration. Type-A cats had weak agglutinins of the IgM class and weak hemolysins which consisted of approximately equal parts of IgG and IgM class. Type-B cats had strong hemagglutinins and hemolysins mostly of the IgM class. Colostral antibodies were detectable in newborns as early as 4 h after birth and their own alloantibody production started at 6-8 weeks of age. The presence of naturally occurring alloantibodies, in particular the anti-A alloantibodies, renders cats susceptible to clinical incompatibility reactions.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
0165-2427
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
38
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
283-95
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:8291206-ABO Blood-Group System,
pubmed-meshheading:8291206-Animals,
pubmed-meshheading:8291206-Animals, Newborn,
pubmed-meshheading:8291206-Cats,
pubmed-meshheading:8291206-Colostrum,
pubmed-meshheading:8291206-Erythrocytes,
pubmed-meshheading:8291206-Female,
pubmed-meshheading:8291206-Immunoglobulin G,
pubmed-meshheading:8291206-Immunoglobulin M,
pubmed-meshheading:8291206-Isoantibodies,
pubmed-meshheading:8291206-Male
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pubmed:year |
1993
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pubmed:articleTitle |
Alloantibodies against A and B blood types in cats.
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pubmed:affiliation |
Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia 19104-6010.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|