Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3-4
pubmed:dateCreated
1994-2-22
pubmed:abstractText
This study characterizes the naturally occurring feline alloantibodies against A and B blood type. All examined type-A and type-B cats had naturally occurring antibodies against erythrocytes of the opposite blood type. In order to determine the class of immunoglobulins, sera from cats were analyzed using incubation with 2-mercaptoethanol (2-ME), immunoprecipitation, and gel filtration. Type-A cats had weak agglutinins of the IgM class and weak hemolysins which consisted of approximately equal parts of IgG and IgM class. Type-B cats had strong hemagglutinins and hemolysins mostly of the IgM class. Colostral antibodies were detectable in newborns as early as 4 h after birth and their own alloantibody production started at 6-8 weeks of age. The presence of naturally occurring alloantibodies, in particular the anti-A alloantibodies, renders cats susceptible to clinical incompatibility reactions.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0165-2427
pubmed:author
pubmed:issnType
Print
pubmed:volume
38
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
283-95
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Alloantibodies against A and B blood types in cats.
pubmed:affiliation
Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia 19104-6010.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't