Linked Life Data

8285923

Source:http://linkedlifedata.com/resource/pubmed/id/8285923

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
1994-2-17
pubmed:abstractText
The determinant trisaccharide of the blood group A, GalNAc alpha 1-3(Fuc alpha 1-2)Gal beta, was modified by treatment of the trisaccharide acetate with phosphorus pentasulphide to convert its acetamide fragment determining the serological difference between antigenic determinants A and B into the thioacetamide derivative. Thionated analogues of the A disaccharide and of GalNAc alpha-glycoside were obtained in a similar way. Interaction of three monoclonal anti-A antibodies with modified antigens was studied using ELISA, the O-->S replacement allowing to evaluate the contribution of the acetamido carbonyl group into the antigen-antibody interaction.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0132-3423
pubmed:author
pubmed:issnType
Print
pubmed:volume
19
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1095-101
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
[Synthesis of thioacetamide analogs of blood group specific trisaccharide A and its fragments].
pubmed:publicationType
Journal Article, English Abstract