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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1994-2-17
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pubmed:abstractText |
Biopsy specimens obtained from 2 patients with monocytoid B cell lymphoma, 7 with mantle zone lymphoma, 7 with small lymphocytic lymphoma or B chronic lymphocytic leukemia, and 6 with hairy cell leukemia were investigated using an immunohistochemical method to detect their immunophenotypic characteristics. Periodate-lysine-paraformaldehyde-fixed frozen biopsies from the lymph node, peripheral blood, bone marrow, spleen, tonsil, lung, and stomach were studied. Monocytoid B cell lymphoma exhibited the immunophenotype of surface(s) IgD-/DRC-1-/Leu-1(CD5)-/Leu-M5(CD11c)-, +/- on the neoplastic cells or neoplastic lesions, mantle zone lymphoma exhibited that of sIgD+/DRC-1++/Leu-1-,+/Leu-M5-, small lymphocytic lymphoma or B chronic lymphocytic leukemia that of Leu-1+/sIgD-,+sIgD-,+/DRC-1- > +Leu-M5-, and hairy cell leukemia that of Leu-M5++/sIgD- >> +/Leu-1- >> +/DRC-1-. We therefore suggest that these four types of lymphomas can be differentiated by a combination of anti-sIgD, DRC-1, Leu-1, and Leu-M5 monoclonal antibodies based on their immunophenotypic characteristics.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
0001-5792
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
90
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
84-9
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:8285023-Bone Marrow,
pubmed-meshheading:8285023-Humans,
pubmed-meshheading:8285023-Immunohistochemistry,
pubmed-meshheading:8285023-Immunophenotyping,
pubmed-meshheading:8285023-Leukemia, Hairy Cell,
pubmed-meshheading:8285023-Leukemia, Lymphocytic, Chronic, B-Cell,
pubmed-meshheading:8285023-Lung,
pubmed-meshheading:8285023-Lymph Nodes,
pubmed-meshheading:8285023-Lymphoma, B-Cell,
pubmed-meshheading:8285023-Palatine Tonsil,
pubmed-meshheading:8285023-Spleen,
pubmed-meshheading:8285023-Stomach
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pubmed:year |
1993
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pubmed:articleTitle |
Immunohistochemical characteristics of monocytoid B cell lymphoma, mantle zone lymphoma, small lymphocytic lymphoma (or B chronic lymphocytic leukemia), and hairy cell leukemia.
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pubmed:affiliation |
Section of Clinical Laboratory, Hospital, National Institute of Radiological Sciences, Chiba, Japan.
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pubmed:publicationType |
Journal Article
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