Linked Life Data

8283347

Source:http://linkedlifedata.com/resource/pubmed/id/8283347

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
1994-2-15
pubmed:abstractText
Morphological changes in cultured utricular supporting cells following streptomycin sulfate (SM) intoxication were investigated using an organ culture system. Utricles of guinea pig were exposed to 30 and 3mg/ml of SM for 1-3 days in culture. The number of lysosomes in the supporting cells increased daily, and mitochondria, myeloid bodies, granules and vesicles were observed within the lysosomes. As these components accumulated in the lysosomes, the number of granules and vesicles in the cytoplasma decreased. Acid phosphatase (AcPase) activity also decreased. After 1-3 days culture with SM, the culture medium was changed to a medium without SM. After removal of SM, the Golgi apparati appeared more developed and AcPase activity was higher. At the same time, lysosomes were markedly decreased in number and the endoplasmic reticulum showed a gradual reproduction. These findings suggest close relationships among the Golgi apparatus, lysosomes, secretory granules and the endplasmic reticulum.
pubmed:language
jpn
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0030-6622
pubmed:author
pubmed:issnType
Print
pubmed:volume
96
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1950-61
pubmed:dateRevised
2011-7-28
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
[Morphological changes in the supporting cells of the utricular macula due to streptomycin intoxication].
pubmed:affiliation
Department of Otolaryngology, Hiroshima University School of Medicine.
pubmed:publicationType
Journal Article, English Abstract, Research Support, Non-U.S. Gov't