Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1994-2-17
pubmed:abstractText
The multiple sclerosis (MS) case-control ratio by state originating from the U.S. veteran series from World War II (Kurtzke Neurology 1979; 29: 1228-1235) was geographically compared with 46 sociogeographic variables from the period 1935-1958. Latitude was, by far, the variable most closely associated with MS in univariate testing. Multivariate analysis by factor analysis revealed that the MS rate was associated with 2 independent settings ("factors"). The first one was defined mainly socioeconomically and was characterized by indicators of higher affluence; better nutrition with a higher meat consumption in particular, and a higher sanitary level were the prominent features. The second MS-related bundle comprised characteristics of a colder climate along with further dietary variables (i.e. a diet low in fish and high in dairy products). The findings suggest a possible interaction of both socioeconomic and geoclimatic features in the etiology of MS; sanitation, diet and climate being of particular interest.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0895-4356
pubmed:author
pubmed:issnType
Print
pubmed:volume
47
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
43-8
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
The risk of multiple sclerosis in the U.S.A. in relation to sociogeographic features: a factor-analytic study.
pubmed:affiliation
Department of Neurology, Academic Teaching Hospital, Darmstadt, Germany.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't