Linked Life Data

8279213

Source:http://linkedlifedata.com/resource/pubmed/id/8279213

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1994-2-9
pubmed:abstractText
The present study is concerned with the critical difference, which may help to judge whether or not the difference between two consecutive measurements with a certain probability (i.e. 95 percent) may be ascribed to natural variation. Knowledge of the applicability of the critical difference in veterinary medicine is sparse and therefore, to justify future use of the critical difference, it is important to know whether or not the critical difference performs as expected. The hypothesis to be tested in this study was that at least 95 percent of the differences between consecutive measurements, that have been obtained in animals where the component measured is known to be unchanged, should be within the critical difference. From previous studies it was known that a low-sodium diet had no influence on the plasma potassium concentration. The critical difference of the plasma potassium concentration in dogs was calculated as 0.5 mmol/l. using weekly measurements of this plasma component in a group of twenty healthy dogs. To test the hypothesis, this value was compared to the differences between consecutive weekly measurements of this plasma component in another group of eight dogs fed a low-sodium diet for five weeks. In agreement with previous studies, the plasma potassium concentration in the eight dogs did not change significantly during the feeding experiment. Of the fourty differences between consecutive weekly measurements, thirty-six were within the critical difference. This number was not different from the number expected from the hypothesis and thus, the critical difference performed as expected.(ABSTRACT TRUNCATED AT 250 WORDS)
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0514-7158
pubmed:author
pubmed:issnType
Print
pubmed:volume
40
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
624-30
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Applicability of the critical difference.
pubmed:affiliation
Small Animal Hospital, Department of Clinical Studies, Royal Veterinary and Agricultural University, Frederiksberg C, Denmark.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't