Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1977-3-21
pubmed:abstractText
In short-term liquid cultures of leukemic blood cells from 60 untreated patients with acute lymphoblastic leukemia (ALL) or acute myeloblastic leukemia (AML) the 3H-thymidine incorporation was measured. After 24, 48 and 72 h of culture, leukemic cells from AML patients consistently showed much higher incorporation values than those from ALL patients. In addition, the cultured cells were studied with the pulse cytophotometer to measure the cell phase distribution of the leukemic cell population. The percentages of cells in S, G2, and M phases in cultures from AML patients were also clearly higher than those from ALL patients. These test methods provide an additional diagnostic aid, especially for those forms of acute leukemia, which remain unclassified by conventional morphological and histochemical criteria.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0001-5792
pubmed:author
pubmed:issnType
Print
pubmed:volume
56
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
321-7
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
Proliferation of leukemic blood cells in short-term liquid cultures. Relevance to the differential diagnosis of acute myeloblastic and lymphoblastic leukemia.
pubmed:publicationType
Journal Article