Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
15
pubmed:dateCreated
1994-2-4
pubmed:abstractText
Fibronectin is a glycoprotein involved in a wide variety of cellular activities, including the development of bone tissues. To study the relevance of fibronectin to the development of ossification of the posterior longitudinal ligament (OPLL) and ossification of the ligamentum flavum (OLF), plasma fibronectin concentrations in 30 consecutive patients with OPLL or OLF and 20 age-and-sex-matched control subjects were measured with an immunonephelometric method. Plasma fibronectin concentrations were significantly elevated in the patients with OPLL or OLF, independently of associated endocrinologic abnormalities, when compared with the control subjects. Because fibronectin is one of the essential factors in endochondral ossification, it is probable that the higher fibronectin concentration in plasma acts as a promoter of the development of OPLL and OLF.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0362-2436
pubmed:author
pubmed:issnType
Print
pubmed:volume
18
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2267-70
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Elevated plasma fibronectin concentrations in patients with ossification of the posterior longitudinal ligament and ossification of the ligamentum flavum.
pubmed:affiliation
Department of Orthopaedic Surgery, Osaka University Medical School, Japan.
pubmed:publicationType
Journal Article, Comparative Study