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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
1994-2-10
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pubmed:abstractText |
Ambient light is the major agent mediating entrainment of circadian rhythms and is also a major factor influencing development and morphogenesis. We show that in Neurospora crassa the expression of clock-controlled gene 2 (ccg-2), a gene under the control of the circadian clock and allelic to the developmental gene easy wettable (eas), is regulated by light in wild-type strains. Light elicits a direct and important physiological effect on ccg-2(eas) expression as demonstrated using several mutant Neurospora strains. In white collar mutants (wc-1 and wc-2) that are "blind" to blue light, ccg-2(eas) mRNA shows no variation following illumination with saturating light. By contrast, ccg-2(eas) mRNA is photoinduced in clock-null strains such as frequency (bd;frq). The results in the clock mutants show that an intact circadian oscillator is not required for light induction of ccg-2(eas). Thus, ccg-2(eas) is subject to a dual regulation that involves separable regulation by light and circadian rhythm.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/8278550-1392609,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8278550-1459460,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8278550-1549784,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8278550-16656687,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8278550-16663152,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8278550-1698652,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8278550-1837560,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8278550-2112267,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8278550-2116012,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8278550-2116813,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8278550-2144609,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8278550-2525233,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8278550-2527354,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8278550-2535546,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8278550-2977186,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8278550-2980965,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8278550-3208743,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8278550-5721155,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8278550-5978549,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8278550-6219280,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8278550-6312838,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8278550-8466189
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0032-0889
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
102
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pubmed:geneSymbol |
ccg-2,
ccg-2(eas)
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1299-305
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pubmed:dateRevised |
2010-9-10
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pubmed:meshHeading |
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pubmed:year |
1993
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pubmed:articleTitle |
The interplay of light and the circadian clock. Independent dual regulation of clock-controlled gene ccg-2(eas).
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pubmed:affiliation |
Dipartimento di Biopatologia Umana, Università di Roma La Sapienza, Italy.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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