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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
|
| pubmed:dateCreated |
1977-3-15
|
| pubmed:abstractText |
A 20mu diameter pore size screen was inserted into an arterio-venous bypass system in heparinized stumptailed monkeys. ADP and serotonin injection resulted in aggregation of platelets on the screen and consecutive increase in pre-screen pressure and decrease in post-screen pressure. From these changes an "aggregation index" was calculated. Bencyclan in doses of 0.5-15 mg/kg inhibited platelet aggregation in vivo. Doses of 20 mg/kg or above showed some hemolytic effect, no other undesirable effects were seen.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0025-7850
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
7
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
439-47
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:827596-Adenosine Diphosphate,
pubmed-meshheading:827596-Animals,
pubmed-meshheading:827596-Bencyclane,
pubmed-meshheading:827596-Cycloheptanes,
pubmed-meshheading:827596-Dose-Response Relationship, Drug,
pubmed-meshheading:827596-Female,
pubmed-meshheading:827596-Haplorhini,
pubmed-meshheading:827596-Macaca,
pubmed-meshheading:827596-Platelet Aggregation
|
| pubmed:year |
1976
|
| pubmed:articleTitle |
Study of platelet aggregation in vivo i. Effect of bencyclan.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|