Linked Life Data

8275967

Source:http://linkedlifedata.com/resource/pubmed/id/8275967

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1994-2-7
pubmed:abstractText
Immunocytochemical localization of the neuronal growth associated protein GAP-43 revealed a dense axonal plexus throughout the neurointermediate lobe of the rat pituitary. These axons were fine, presumably monoaminergic fibers, whereas magnocellular neurosecretory axons did not appear to contain detectable GAP-43. These experiments also revealed the presence of an extensive nerve plexus within the anterior lobe. Fine beaded fibers were present throughout the parenchyma of the anterior lobe, and punctate staining suggestive of nerve terminals was seen surrounding numerous endocrine cells. Nerve fibers did not appear to cross directly between the intermediate and anterior lobes, but rather entered the anterior lobe directly from its margins or in association with blood vessels. Preabsorption of antisera with GAP-43 purified from neonatal rat brain completely eliminated immunoreactivity. These findings confirm the existence of a direct innervation of the anterior pituitary of the rat; moreover, the presence of GAP-43 in these fibers suggests that they may be capable of growth and terminal reorganization in the adult animal.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0013-7227
pubmed:author
pubmed:issnType
Print
pubmed:volume
134
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
503-6
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Innervation of the rat anterior and neurointermediate pituitary visualized by immunocytochemistry for the growth-associated protein GAP-43.
pubmed:affiliation
Dept. of Biology, Montana State University, Bozeman 59717.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't