Linked Life Data

8275891

Source:http://linkedlifedata.com/resource/pubmed/id/8275891

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1994-2-7
pubmed:abstractText
Besides imaging NMR can obtain spectrum reflecting brain tissues components able to resound. Some of these take an active part in a CNS metabolism: such are H (in water) and P (in MPA-TPA, etc.). This new investigating method already showed interest in vitro (tissues cultures) and in vivo (muscular metabolism) studies. Its application to cerebral metabolism studies are going to spread thanks to technological advances (magnetic field more powerful: air gap broad enough for human head passage). The first results of this investigation, in 5 SDAT patients diagnosed with respectively international inclusion criteria (NINCDS-ADRDA) and exclusion ones (such as XR Scan and SPECT exploration), are presented; they are divided into two different groups showing PME (phosphomonoesters) peak dropped to 3.2 or 1.8 in one part, and raised to 15.5 till 27 ppm (parts by million: conventional unit dealing with substances concentration) as the normal range is set at about 7 +/- 4.5 ppm. Such PME changes have showed in an other B. Roussel's study to be a good biological index correlated with the age and the CNS state; these results seem to be of interest, mainly (that must be emphasized) as this technique is quite non intrusive and non irradiating.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0013-7006
pubmed:author
pubmed:issnType
Print
pubmed:volume
19
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
29-35
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
[Value of NMR spectroscopy in exploring the cerebral metabolism of patients affected by Alzheimer's disease].
pubmed:affiliation
Psychiatre des Hôpitaux, SHU, CHS du Vinatier, Bron.
pubmed:publicationType
Journal Article, English Abstract