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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1994-2-8
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pubmed:abstractText |
The present study was designed to evaluate the kinetics of acetaldehyde (ACT) and and its action on the cardiovascular system in rats. ACT (3, 6, 12 mg/kg i.p.) causes accumulation of this metabolite in the blood, at a concentration corresponding to that obtained from ethanol metabolism after its administration in doses of 1, 2, 4 g/kg p.o., respectively. After intraperitoneal injection of ACT there were no significant changes in blood pressure and heart rate in comparison to the control group. It appears that, in rats, ACT has no influence on the function of the cardiovascular system after the ingestion of ethanol.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
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pubmed:issn |
0735-0414
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
28
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
529-33
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:8274176-Acetaldehyde,
pubmed-meshheading:8274176-Alcohol Drinking,
pubmed-meshheading:8274176-Animals,
pubmed-meshheading:8274176-Blood Pressure,
pubmed-meshheading:8274176-Cardiovascular System,
pubmed-meshheading:8274176-Dose-Response Relationship, Drug,
pubmed-meshheading:8274176-Ethanol,
pubmed-meshheading:8274176-Heart Rate,
pubmed-meshheading:8274176-Hemodynamics,
pubmed-meshheading:8274176-Male,
pubmed-meshheading:8274176-Rats,
pubmed-meshheading:8274176-Rats, Wistar
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pubmed:year |
1993
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pubmed:articleTitle |
Lack of effect of acetaldehyde on the cardiovascular system in rats.
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pubmed:affiliation |
Department of Pharmacodynamics, Medical Academy, Bialystok, Poland.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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