Linked Life Data

827363

Source:http://linkedlifedata.com/resource/pubmed/id/827363

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
1977-3-31
pubmed:abstractText
Two series of experiments were carried out on chick embryos, stages 24 to 28 pairs of somites. (1) Denuded mesenchyme obtained from leg presumptive area previously treated with nitrogen mustard, was grafted into the right flank of embryos, stages 15 to 24 pairs of somites. (2) Conversely, denuded mesenchyme was implanted into the flank of nitrogen mustard-treated embryos. In most of the embryos, a supernumerary abnormal limb appeared; 58% of the legs produced in the first set of experiments had distal parts, whereas only 15% of the legs in the second set of experiments showed toes. Most of these legs had a hemimelic aspect or were reduced to stumps. This study demonstrates that deficiencies localised in the ectodermal apical part of the bud may be responsible for the stumpy limb defect.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0567-655X
pubmed:author
pubmed:issnType
Print
pubmed:day
27
pubmed:volume
283
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1241-4
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
[Genesis of malformations of the distal parts of chick embryo extremities (adactylia, hemimelia)].
pubmed:publicationType
Journal Article, English Abstract