Linked Life Data

8267626

Source:http://linkedlifedata.com/resource/pubmed/id/8267626

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1994-1-25
pubmed:abstractText
Available data obtained so far has indicated that hepoxilin formation from 12-HPETE is catalyzed by hemin and hemoglobin and is not affected through heating of these ferri-heme compounds suggestive of nonenzymatic processes. The present paper demonstrates for the first time that 12-HPETE is transformed into the hepoxilins A3 and B3 by intact cells (skin subcutis layer) and slices of several tissues (brain hippocampus and pineal gland) and that this transformation is inhibited by tissue boiling, indicating an enzymatic catalysis. The tissues employed are pharmacologically responsive to hepoxilins and hence the present data offer biochemical support of a potential biological role for the hepoxilins in these tissues.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0006-291X
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
197
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
869-73
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Enzymatic formation of hepoxilins A3 and B3.
pubmed:affiliation
Research Institute, Hospital for Sick Children, Toronto, Canada.
pubmed:publicationType
Journal Article, In Vitro, Research Support, Non-U.S. Gov't