Linked Life Data

8266965

Source:http://linkedlifedata.com/resource/pubmed/id/8266965

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
1994-1-21
pubmed:abstractText
The stability of fluconazole in an extemporaneously prepared oral liquid was studied. An aqueous liquid formulation of fluconazole was prepared by reconstituting the powder from triturated 100-mg tablets with deionized water; the nominal fluconazole concentration was 1 mg/mL. Glass vials of the liquid were stored in the dark at 4, 23, and 45 degrees C and sampled immediately and after 1, 2, 3, and 15 days. Samples were analyzed in duplicate for fluconazole concentration by high-performance liquid chromatography. The concentration of fluconazole was virtually unchanged under all the storage conditions. The results were confirmed by analysis of variance. Fluconazole 1 mg/mL in an extemporaneously prepared oral liquid was stable at 4, 23, and 45 degrees C for up to 15 days.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0002-9289
pubmed:author
pubmed:issnType
Print
pubmed:volume
50
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2366-7
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Stability of fluconazole in an extemporaneously prepared oral liquid.
pubmed:affiliation
School of Pharmacy, University of Wyoming, Cheyenne.
pubmed:publicationType
Journal Article