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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1977-2-26
|
| pubmed:abstractText |
The effects of a semidominant autosomal meiotic mutant, orientation disruptor (symbol: ord), located at 2-103.5 on the genetic map and in region 59B-D of the salivary map, have been examined genetically and cytologically. The results are as follows. (1) Crossing over in homozygous females is reduced to about seven percent of controls on all chromosomes, with the reduction greatest in distal regions. (2) Crossing over on different chromosomes is independent. (3) Reductional nondisjunction of any given chromosome is increased to about thirty percent of gametes from homozygous females. The probability of such nondisjunction is the same among exchange and nonexchange tetrads with the exception that a very proximal exchange tends to regularize segregation. (4) Equational nondisjunction of each chromosome is increased to about ten percent of gametes in homozygous females; this nondisjunction is independent of exchange. (5) The distributive pairing system is operative in homozygous females. (6) In homozygous males, reductional nondisjunction of each chromosome is increased to about ten percent, and equational nondisjunction to about twenty percent, of all gametes. (7) Cytologically, two distinct meiotic divisions occur in spermatocytes of homozygous males. The first division looks normal although occasional univalents are present at prophase I and a few lagging chromosomes are seen at anaphase I. However, sister chromatids of most chromosomes have precociously separated by metaphase II. Possible functions of the ord(+) gene are considered.
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| pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/826453-16589770,
http://linkedlifedata.com/resource/pubmed/commentcorrection/826453-17246287,
http://linkedlifedata.com/resource/pubmed/commentcorrection/826453-17247620,
http://linkedlifedata.com/resource/pubmed/commentcorrection/826453-17248182,
http://linkedlifedata.com/resource/pubmed/commentcorrection/826453-17248428,
http://linkedlifedata.com/resource/pubmed/commentcorrection/826453-4376098,
http://linkedlifedata.com/resource/pubmed/commentcorrection/826453-4624779,
http://linkedlifedata.com/resource/pubmed/commentcorrection/826453-4624918,
http://linkedlifedata.com/resource/pubmed/commentcorrection/826453-4625747,
http://linkedlifedata.com/resource/pubmed/commentcorrection/826453-4633612,
http://linkedlifedata.com/resource/pubmed/commentcorrection/826453-5003954,
http://linkedlifedata.com/resource/pubmed/commentcorrection/826453-6029974
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Nov
|
| pubmed:issn |
0016-6731
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
84
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
545-72
|
| pubmed:dateRevised |
2010-9-3
|
| pubmed:meshHeading |
pubmed-meshheading:826453-Animals,
pubmed-meshheading:826453-Crossing Over, Genetic,
pubmed-meshheading:826453-Drosophila melanogaster,
pubmed-meshheading:826453-Female,
pubmed-meshheading:826453-Genes, Dominant,
pubmed-meshheading:826453-Homozygote,
pubmed-meshheading:826453-Male,
pubmed-meshheading:826453-Meiosis,
pubmed-meshheading:826453-Mutation,
pubmed-meshheading:826453-Recombination, Genetic,
pubmed-meshheading:826453-Sex Factors
|
| pubmed:year |
1976
|
| pubmed:articleTitle |
Orientation disruptor (ord): a recombination-defective and disjunction-defective meiotic mutant in Drosophila melanogaster.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|