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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1994-1-24
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pubmed:abstractText |
Hematologic data from 1,039 persons who participated in the Miyazaki Cohort study on human T-cell lymphotropic virus type-I (HTLV-I) infection were analyzed. Individuals were classified by HTLV-I antibody status and the presence of abnormal lymphocytes (Ably). We identified several differences in selected leukocyte populations: lymphocyte percent was higher among the HTLV-I carriers with Ably (36.5 +/- 2.0%, n = 29) compared with the carriers without Ably (33.1 +/- 0.6%, n = 299) and the seronegatives 36.4 +/- 0.4%, n = 711) (p = 0.04). Conversely, there was a trend of decreasing eosinophil percent among both carrier groups with the lowest percent among carriers with Ably (1.8 +/- 0.5%) compared with the seronegatives (2.8 +/- 0.1%) (p = 0.05). Mean basophil percent was decreased among both carriers groups (p = 0.09). Additionally, red cell count was elevated among the carriers with Ably (461 +/- 7 x 10(4)/mm3) compared with the seronegatives (446 +/- 2 x 10(4)/mm3) (p = 0.03). The HTLV-I carriers with Ably had lower serum albumin (4.39 +/- 0.05 g%) compared with the seronegatives (4.47 +/- 0.01 g%) (p = 0.10). These alterations may be a consequence of HTLV-I infection, with the greatest changes among carriers with Ably, a subset thought to be at risk for developing adult T-cell leukemia.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0894-9255
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
92-7
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:8263758-Alanine Transaminase,
pubmed-meshheading:8263758-Alcohol Drinking,
pubmed-meshheading:8263758-Aspartate Aminotransferases,
pubmed-meshheading:8263758-Carrier State,
pubmed-meshheading:8263758-Cohort Studies,
pubmed-meshheading:8263758-Erythrocyte Count,
pubmed-meshheading:8263758-Female,
pubmed-meshheading:8263758-HTLV-I Infections,
pubmed-meshheading:8263758-Hematocrit,
pubmed-meshheading:8263758-Hemoglobins,
pubmed-meshheading:8263758-Humans,
pubmed-meshheading:8263758-Leukocyte Count,
pubmed-meshheading:8263758-Lymphocytes,
pubmed-meshheading:8263758-Male,
pubmed-meshheading:8263758-Middle Aged,
pubmed-meshheading:8263758-Serum Albumin,
pubmed-meshheading:8263758-Smoking
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pubmed:year |
1994
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pubmed:articleTitle |
Changes in hematologic parameters among Japanese HTLV-I carriers.
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pubmed:affiliation |
Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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