Linked Life Data

8262212

Source:http://linkedlifedata.com/resource/pubmed/id/8262212

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1994-1-26
pubmed:abstractText
The cell cycle of eukaryotic cells is strictly regulated. This regulation is performed by a serine/threonine kinase. The different functions of this kinase in the cell cycle are modulated by different cyclins, which fluctuate in concentration ('cycle') during the different stages of the cell cycle. Using yeast as a model organism we show here that the activity of the multifunctional proteinase, the proteasome, is directly connected to the function of the mitotic cyclin Clb2. Our studies indicate that the proteasome is the proteolytic regulator of this cyclin and thus a central regulator of the cell cycle.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0014-5793
pubmed:author
pubmed:issnType
Print
pubmed:day
20
pubmed:volume
336
pubmed:geneSymbol
CLB2, GAL1, PRE1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
34-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Proteasome and cell cycle. Evidence for a regulatory role of the protease on mitotic cyclins in yeast.
pubmed:affiliation
Institut für Biochemie der Universität Stuttgart, Germany.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't