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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1994-1-21
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pubmed:abstractText |
We have investigated the expression of bcl-2 protein in a panel of small cell lung carcinoma (SCLC) cells lines. Five of six cell lines examined expressed relatively high levels of bcl-2 protein and transcripts. The bcl-2 expression in SCLC cells, however, was not always associated with myc expression. Since dysregulation of bcl-2 may be involved in the course of tumorigenesis and/or in the acquisition of drug resistance of tumor cells, the expression of bcl-2 in SCLC cells may become an important indicator in the prognosis or treatment of SCLC.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
|
pubmed:issn |
0008-5472
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
1
|
pubmed:volume |
54
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
6-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8261463-Carcinoma, Small Cell,
pubmed-meshheading:8261463-Humans,
pubmed-meshheading:8261463-Lung Neoplasms,
pubmed-meshheading:8261463-Prognosis,
pubmed-meshheading:8261463-Proto-Oncogene Proteins,
pubmed-meshheading:8261463-Proto-Oncogene Proteins c-bcl-2,
pubmed-meshheading:8261463-Proto-Oncogene Proteins c-myc,
pubmed-meshheading:8261463-Tumor Cells, Cultured
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pubmed:year |
1994
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pubmed:articleTitle |
Expression of bcl-2 in small cell lung carcinoma cells.
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pubmed:affiliation |
Department of Pediatrics, University of Pennsylvania, School of Medicine, Philadelphia 19104.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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