Linked Life Data

826024

Source:http://linkedlifedata.com/resource/pubmed/id/826024

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
1977-1-29
pubmed:abstractText
In agar diffusion tests 2603 bacterial strains of species known to cause urinary tract infections were tested routinely in regard to their sensitivity towards Terizidon, a derivative of cycloserine. In order to relate the results which were obtained in terms of the diameter of the inhibiton zone, to the minimal inhibitory concentrations (MIC), 304 of these strains were tested additionally in agar dilution tests. The MICs of the other strains were estimated from the results of these tests. Since it is known that after the oral administration of 500 mg Terizidon the urine contains, on average, more than 128 mug/ml Terizidon for 12 hours and longer, it may be concluded from the results of this investigation that 75% of the strains of E. coli and Citrobacter, 45% of enterobacter, 40% of Proteus mirabilis and enterococci, 35% of the indole-positive Proteus strains and 30% of Pseudomonas aeruginosa would have been successfully attacked by Terizidon in the case or urinary tract infections. By contrast, Klebsiella must be reagarded as being completely resistant to this antibiotic. It follows that the administration of Terizidon is mainly indicated in the treatment of acute urinary tract infections with E. coli as the predominant causative agent.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0043-5325
pubmed:author
pubmed:issnType
Print
pubmed:day
28
pubmed:volume
88
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
355-60
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
[Sensitivity of bacteria causing urinary tract infections towards terizidon (author's transl)].
pubmed:publicationType
Journal Article, English Abstract