Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
1994-1-19
pubmed:abstractText
Fluorescence spectra are recorded from the cortex and nucleus of the same human lenses [clear and cataracta brunescens (nigra) with colorless cortex]. When comparing clear cortices with either the harder nucleus of a clear lens, or a cataracta brunescens for a given excitation wavelength, a shift of the fluorescence maxima of the nucleus to longer wavelengths is observed. The shift appears to be independent of the degree of coloring since it is very similar for different nuclei, and it is not increased in cataracta nigra. The fluorescence intensities are similar when comparing the clear cortex of clear lenses and cataracta brunescens. For the nuclei, however, the intensity increases by up to four to six times with increasing coloring. For constant excitation wavelength, the fluorescence band maximum of the nucleus (of clear lenses and of cataracta brunescens) exhibits roughly the same shift to longer wavelengths as that of the cortex. Upon 320 nm excitation the fluorescence intensity of a cataracta nigra is about twice that of a clear lens of juvenile age. Upon 380 nm excitation the factor increases to four. Therefore in older and colored lens nuclei a red shift of the fluorescence maximum with increasing excitation wavelength is observed. We discuss whether or not the changes in the molecular proteins, in addition to advanced glycolization end products, may be responsible for the different fluorescence properties (and the brown color) with increasing age.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0721-832X
pubmed:author
pubmed:issnType
Print
pubmed:volume
231
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
656-61
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
Different regional changes of fluorescence spectra of clear human lenses and nuclear cataracts.
pubmed:affiliation
Eye Clinic, Heinrich-Heine Universität Düsseldorf, Germany.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't