Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
44
pubmed:dateCreated
1977-1-25
pubmed:abstractText
In 18 patients with Crohn's disease, 28 patients with ulcerative colitis, 24 patients with acute enteritis and in 68 healthy adults lipid A antibody titers were determined by the passive hemolysis test. In addition O antibody titers to polyvalent Escherichia coli, Klebsiella, Proteus and Pseudomonas aeruginosa antigens were measured by indirect hemagglutination. The patients with Crohn's disease showed a statistically significant elevation of the lipid A antibody titers compared with each of the three other groups investigated. The O antibody titers for the four polyvalent antigens were higher in the patients with Crohn's disease than in the other groups. The results indicate that Enterobacteriaceae are involved in the pathogenesis of Crohn's disease. Thus, long-term treatment with wide spectrum antibiotics seems to be justified. The determination of lipid A antibody titers may be useful in differentiating between Crohn's disease and ulcerative colitis on diagnosis.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0025-8458
pubmed:author
pubmed:issnType
Print
pubmed:day
29
pubmed:volume
71
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1898-902
pubmed:dateRevised
2007-8-13
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
[Lipid A antibody titers and O antibody titers in Crohn's disease, ulcerative colitis and acute enteritis (author's transl)].
pubmed:publicationType
Journal Article, Comparative Study, English Abstract