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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
1994-1-10
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pubmed:abstractText |
Pseudomonas aeruginosa has been located in the endobronchiolar spaces of patients with cystic fibrosis where nutrients may be limited. In these sites it is thought that adaptation of the pathogen might occur and growth factors, present in relative excess, may thus promote survival of the organism. Auxotrophy of pulmonary isolates of P aeruginosa has previously been shown to be a feature of cystic fibrosis and chronic lung sepsis; auxotrophic isolates have additional nutritional requirements to the prototrophic "wild types" of the species. A study was therefore carried out to determine whether the proportion of auxotrophs differs between stable and acutely ill patients, or correlates with the extent of underlying disease.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/8256228-13184240,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8256228-14045224,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8256228-1624122,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8256228-1929327,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8256228-2107198,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8256228-2281431,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8256228-2425090,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8256228-2513765,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8256228-2701477,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8256228-2701927,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8256228-3497170,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8256228-351182
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0040-6376
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
48
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1002-5
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pubmed:dateRevised |
2010-3-24
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pubmed:meshHeading |
pubmed-meshheading:8256228-Acute Disease,
pubmed-meshheading:8256228-Adolescent,
pubmed-meshheading:8256228-Adult,
pubmed-meshheading:8256228-Aged,
pubmed-meshheading:8256228-Cystic Fibrosis,
pubmed-meshheading:8256228-Female,
pubmed-meshheading:8256228-Growth Substances,
pubmed-meshheading:8256228-Humans,
pubmed-meshheading:8256228-Male,
pubmed-meshheading:8256228-Methionine,
pubmed-meshheading:8256228-Middle Aged,
pubmed-meshheading:8256228-Mutation,
pubmed-meshheading:8256228-Pseudomonas Infections,
pubmed-meshheading:8256228-Pseudomonas aeruginosa,
pubmed-meshheading:8256228-Sputum,
pubmed-meshheading:8256228-Time Factors
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pubmed:year |
1993
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pubmed:articleTitle |
Adult cystic fibrosis: association of acute pulmonary exacerbations and increasing severity of lung disease with auxotrophic mutants of Pseudomonas aeruginosa.
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pubmed:affiliation |
Department of Cystic Fibrosis, Royal Brompton Hospital, London.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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